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High-resolution Fiber-optic Microendoscopy for in situ Cellular Imaging
Published on: January 11, 2011
LED-based Hyperspectral Endoscopic Imaging
Naeeme Modir1, Maysam Shahedi1, James Dormer1
1Center for Imaging and Surgical Innovation, Department of Bioengineering, University of Texas at Dallas, Richardson, TX.
Abstract:
Hyperspectral endoscopy can offer multiple advantages as compared to conventional endoscopy. Our goal is to design and develop a real-time hyperspectral endoscopic imaging system for the diagnosis of gastrointestinal (GI) tract cancers using a micro-LED array as an in-situ illumination source. The wavelengths of the system range from ultraviolet to visible and near infrared. To evaluate the use of the LED array for hyperspectral imaging, we designed a prototype system and conducted ex vivo experiments using normal and cancerous tissues of mice, chicken, and sheep. We compared the results of our LED-based approach with our reference hyperspectral camera system. The results confirm the similarity between the LED-based hyperspectral imaging system and the reference HSI camera. Our LED-based hyperspectral imaging system can be used not only as an endoscope but also as a laparoscopic or handheld devices for cancer detection and surgery.

