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Salt processing: A unique and classic technology for Chinese medicine processing.

Ajiao Hou¹, Jiahao Lv¹, Shihao Zhang¹

¹Key Laboratory of Basic and Application Research of Beiyao, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin, China.

Frontiers in Pharmacology

|February 16, 2023

Summary

Salt processing of Traditional Chinese Medicine (TCM) modifies properties to enhance efficacy and reduce toxicity. This review highlights salt processing

Keywords:

chemical composition in vivo behavior pharmacodynamic effect salt processing traditional Chinese medicine

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Area of Science:

Pharmacology
Traditional Chinese Medicine
Chemical Engineering

Background:

Traditional Chinese Medicine (TCM) processing is based on extensive clinical experience.
Processing alters TCM properties, enhancing efficacy and reducing toxicity for safe medication.
Salt processing is a key TCM technique with significant impacts.

Purpose of the Study:

To review recent advancements in TCM salt processing.
To analyze the influence of salt processing on TCM's chemical composition, pharmacodynamics, and in vivo behavior.
To identify research gaps and suggest future directions for TCM salt processing.

Main Methods:

Literature review of scientific databases (SciFinder Scholar, CNKI, Google Scholar, Baidu Scholar).
Consultation of Chinese herbal classics and the Chinese Pharmacopoeia.
Classification and summarization of research on salt processing methods, excipients, and effects.

Main Results:

Salt processing can direct TCM into the kidney channel, enhancing Yin-nourishing and fire-reducing effects.
Salt processing demonstrably alters the chemical composition, pharmacological effects, and in vivo behavior of TCM.
Specific examples of salt processing's impact on TCM efficacy were identified.

Conclusions:

Salt processing is a valuable technique for optimizing TCM.
Further research is needed to standardize excipient dosage and post-processing quality standards.
Investigating the link between chemical changes and enhanced efficacy is crucial for understanding salt processing principles and innovation.