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Published on: October 6, 2023
Snakebite envenoming in Brazilian children: clinical aspects, management and outcomes
Isadora S Oliveira1, Manuela B Pucca2,3, Felipe A Cerni3
1Department of BioMolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, São Paulo 14040-903, Brazil.
Insights
Snakebite envenoming is a neglected tropical disease affecting millions globally. Pediatric snakebites in Brazil are severe, posing challenges due to limited epidemiological data on treatment effectiveness and outcomes.
Area of Science:
- * Tropical Medicine
- * Pediatric Medicine
- * Epidemiology
Background:
- * Snakebite envenoming is a significant global health issue, classified as a neglected tropical disease, causing substantial mortality and morbidity worldwide.
- * In Brazil, snakebites affect approximately 30,000 individuals annually, with children representing about 15% of cases and facing disproportionately severe outcomes.
- * Pediatric snakebite envenoming presents unique challenges due to smaller body mass, leading to more severe complications compared to adults, despite lower incidence.
Approach:
- * This review synthesizes current knowledge on pediatric snakebite envenoming in Brazil.
- * It examines epidemiological data, clinical presentations, and management strategies specific to children.
- * The study highlights the difficulties in assessing treatment effectiveness and emergency care quality due to data limitations.
Key Points:
- * Children experience more severe outcomes from snakebite envenoming due to physiological differences.
- * Lack of comprehensive epidemiological data hinders effective evaluation of pediatric snakebite management and outcomes in Brazil.
- * Addressing these data gaps is crucial for improving emergency medical services for children affected by snakebites.
Conclusions:
- * Pediatric snakebite envenoming in Brazil requires focused attention due to its severity and the challenges in managing affected children.
- * Improved data collection and research are essential to enhance treatment protocols and outcomes for children suffering from snakebites.
- * Further investigation into the specific characteristics, management, and long-term sequelae of snakebite envenoming in Brazilian children is warranted.
Abstract:
Snakebite envenoming is currently considered a neglected tropical disease, which affects over 5 million people worldwide, and causes almost 150 000 deaths every year, as well as severe injuries, amputations and other sequelae. Snakebite envenoming in children, although proportionally less frequent, is generally more severe, and represents an important challenge for pediatric medicine, since they often result in worse outcomes. In Brazil, given its ecological, geographic and socioeconomic characteristics, snakebites are considered an important health problem, presenting approximately 30 000 victims per year, approximately 15% of them in children. Even with low snakebite incidence, children tend to have higher snakebite severity and complications due to the small body mass and same venom volume inoculated in comparison to adults, even though, due to the lack of epidemiological information about pediatric snakebites and induced injuries, it is difficult to measure the treatment effectiveness, outcomes and quality of emergency medical services for snakebites in children. In this review, we report how Brazilian children are affected by snakebites, describing the characteristics of this affected population, clinical aspects, management, outcomes and main challenges.
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