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Biomarkers: Role and Scope in Neurological Disorders
Vivek Kumar Sharma1,2, Thakur Gurjeet Singh3, Vineet Mehta2
1Chitkara College of Pharmacy, Chitkara University, Chandigarh, Punjab, 140401, India.
Developing biomarkers is crucial for understanding neurological disorders and improving treatments. These markers aid in diagnosis, track disease progression, and predict therapeutic responses, overcoming current research limitations.
Area of Science:
- Neuroscience
- Biomarker Research
- Translational Medicine
Background:
- Neurological disorders represent a significant global health burden, causing mortality and morbidity.
- Current treatments are limited by poor diagnosis, incomplete understanding of disease pathophysiology, and challenges in translating preclinical findings to clinical applications.
- Biomarkers offer a promising avenue to address these limitations in neurological disease management.
Purpose of the Study:
- To review existing biomarkers for various neurological disorders.
- To highlight the potential of biomarker development in advancing the understanding of neurological disease pathophysiology.
- To support the exploration of novel therapeutic targets for effective neurological interventions.
Main Methods:
- Literature review of existing neurological disorder biomarkers.
- Analysis of challenges and opportunities in biomarker identification and validation for neurological conditions.
- Discussion of the role of biomarkers in improving diagnosis, prognosis, and treatment response prediction.
Main Results:
- Biomarker development is essential for overcoming diagnostic and therapeutic hurdles in neurological disorders.
- Existing biomarkers aid in assessing physiological processes and pathological progression.
- Biomarkers can indicate clinical and pharmacological responses to interventions.
Conclusions:
- Biomarker research is highly desired to improve the understanding and treatment of complex neurological disorders.
- Development of reliable biomarkers can facilitate better patient stratification and personalized medicine approaches.
- Further research into biomarkers is critical for designing effective therapeutic strategies and improving patient outcomes.
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