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Updated: Aug 9, 2025

A Mouse Model of Mechanotransduction-driven, Human-like Hypertrophic Scarring
Published on: November 29, 2024
Addressing the Physical and Mental Impacts of Postsurgical Scarring Among Transgender and Gender Diverse People
Kanika Kamal1,2, Jason J Li1, Alex S Keuroghlian3,4
1Harvard Medical School, Boston, Massachusetts, USA.
Abstract:
Few studies have considered the diverse mental and physical health impacts of scarring among transgender and gender diverse (TGD) patients after medically necessary gender-affirming surgery (GAS). For some TGD patients, post-GAS scarring may exacerbate gender dysphoria. For others, it is a physical representation of authenticity. The dearth of research or validated instruments capturing the diversity of priorities and concerns pre- and post-GAS hinders providers' ability to deliver optimal clinical care throughout the gender-affirmation process and impedes progress for evidence-based policy change regarding post-GAS scar treatment. This article provides suggestions for future research directions to address post-GAS scar-related health needs.
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