Recent advances in MOF-bio-interface: a review

Area of Science:

• Materials Science
• Biotechnology
• Interface Engineering

Background:

• Metal-organic frameworks (MOFs) offer tunable properties for diverse applications.
• Biomacromolecules and living systems are crucial but face stability and efficiency challenges.
• Existing MOF applications are limited in harsh environments.

Approach:

• This review systematically examines MOF-bio-interface engineering strategies.
• It summarizes MOF interactions with proteins, polysaccharides, DNA, cells, microbes, and viruses.
• The review analyzes current limitations and future research trajectories.

Key Points:

• MOF-bio-interface engineering overcomes biomacromolecule and living system limitations.
• Specific interfaces discussed include MOFs with enzymes, non-enzymatic proteins, DNA, and cellular entities.
• This approach enhances stability, recyclability, and efficiency in challenging conditions.

Conclusions:

• MOF-bio-interface engineering presents a promising strategy for advancing life and material sciences.
• Future research should focus on overcoming current limitations and exploring novel applications.
• This field holds potential for significant innovation in biomaterials and bio-interfaces.