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Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity

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Lung cancer embolization causing acute limb ischemia: a case report.

Syed Mohammad Asim Hussain¹

¹Frimley Park Hospital, Portsmouth Road, Camberley, GU16 7UJ, Frimley, UK. mbch9sh4@doctors.org.uk.

Journal of Medical Case Reports

|February 16, 2023

Summary

This rare case highlights lung cancer metastasizing via the bloodstream, causing limb-threatening ischemia. Early intervention with embolectomy and fasciotomies saved the limb, suggesting prophylactic antithrombotic therapy for high-risk tumors.

Keywords:

Embolectomy Embolization Fasciotomy Limb ischemia Lung cancer Tumor embolism Vascular

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Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

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Published on: September 22, 2020

Area of Science:

Cardiovascular Surgery
Oncology
Vascular Surgery

Background:

Acute tumor embolism to the popliteal artery causing limb ischemia is a rare complication of advanced cancer.
Tumors typically embolize to the pulmonary circulation; systemic embolization is uncommon.
Large, left atrium-invading lung cancer can fragment and disseminate into systemic circulation.

Observation:

A 62-year-old male with advanced lung cancer presented with acute limb-threatening ischemia.
CT angiogram revealed left popliteal artery occlusion and emboli in the superior mesenteric and right renal arteries.
Emergency popliteal embolectomy and calf fasciotomies were performed, successfully saving the limb.

Findings:

Successful limb salvage via popliteal embolectomy and fasciotomies in a case of systemic tumor embolism.
Demonstrated unique tumor dissemination pattern involving multiple arterial beds.
Highlighted the effectiveness of surgical intervention in acute limb ischemia secondary to tumor embolism.

Implications:

Tumors invading the bloodstream should be considered a high risk for systemic embolization.
Prophylactic antithrombotic therapy may be beneficial in preventing major morbidity from tumor emboli.
This case underscores the importance of considering rare embolic sources in acute limb ischemia.