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Updated: Aug 9, 2025

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Comparison of hematological parameters among chronic periodontitis patients and healthy individuals
Chris Noel Timothy1, Arvina Rajasekar1
1Departments of Periodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Abstract:
Some of the most common oral disorders are periodontal disease. Variation in hematological parameters in chronic periodontitis patients could affect the type of treatment and its overall outcomes. Comparing and evaluating the hematological parameters in people with chronic periodontitis and the general population was the aim of this study. 100 individuals with chronic periodontitis (Group I) and 100 individuals in clinically good health participated in the study (Group II). Hemoglobin (Hb), random blood sugar (RBS), bleeding time (BT), and clotting time (CT) were evaluated and compared between the two groups. In contrast to patients with chronic periodontitis (8.934 ± 2.0), in healthy patients, the mean Hb concentrations were found to be higher (13.435 ± 1.8). In comparison to healthy individuals (98.98 ± 25.42), patients with chronic periodontitis had a higher mean value for RBS (112.14 ± 47.5). In contrast to the healthy population (BT = 2.654 ± 13.36, CT = 6.057 ± 0.267), patients with chronic periodontitis had shorter mean BT and CT (BT = 0.301 ± 0.07, CT = 2.84 ± 0.6058). Hematological factors and the population's periodontal health were discovered to be significantly associated (P = 0.001). Within the constraints of the continuing investigation, it was shown that among people with chronic periodontitis, Hb levels, BT, and CT were reduced, while blood glucose levels were increased.

