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[Retracted] Mitochondrial DNA induces inflammation and increases TLR9/NF‑κB expression in lung tissue

Jian-Zheng Zhang1, Zhi Liu1, Jia Liu1

  • 1Department of Orthopedics, Beijing Army General Hospital, Dongcheng, Beijing 100700, P.R. China.

International Journal of Molecular Medicine
|February 17, 2023
PubMed

Insights

This paper has been retracted due to duplicated western blotting images. The data was previously published, leading to concerns about scientific integrity and data presentation in molecular medicine research.

Area of Science:

  • Molecular Biology
  • Immunology

Context:

  • Concerns were raised regarding the originality of data presented in a published study.
  • Specific western blotting images in Fig. 4 were found to be strikingly similar to previously published data.

Purpose:

  • To address allegations of data duplication and plagiarism.
  • To maintain the integrity of scientific publications.

Summary:

  • The study is retracted because western blotting images in Fig. 4 were previously published in another journal (J Clin Invest 112:1235-1243, 2003).
  • The authors did not provide an explanation when contacted by the editorial office.
  • The findings highlight the importance of rigorous image verification in scientific publishing.

Impact:

  • Retraction upholds scientific standards and prevents the dissemination of potentially misleading information.
  • This case underscores the critical role of peer review and reader vigilance in scientific integrity.
  • Ensures the reliability of the scientific record in molecular medicine.
Keywords:
Toll-like receptormacrophagemitochondrial DNAnuclear factor-κBsystemic inflammatory response syndrome

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