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The Use of a Dehydrated Complete Human Placental Membrane Allograft for Mohs Surgical Defects of the Nose
Kelly M Wilmas1, Jigar Patel2, Sirunya Silapunt3
1Department of Dermatology, The University of California San Francisco, San Francisco, California.
Background:
Repair options for Mohs surgical defects include primary closure, flap or graft, or healing by second intention. These options may not be optimal in all cases. A dehydrated complete human placental membrane (dCHPM) allograft may serve as an alternative repair option.
Objective:
To assess the aesthetic and functional outcomes of an alternative repair technique for Mohs surgical defects of the nose.
Methods:
Twenty patients with Mohs surgical defects of the nose repaired with a dCHPM allograft were retrospectively identified. Photographs were used to demonstrate surgical technique and outcomes. Two blinded observers evaluated final outcomes using the Patient and Observer Scar Assessment Scale.
Results:
Observers rated the scar outcome a combined mean score of 8.4 ± 3.2 (scale 5-50). Patients rated their outcomes a mean of 12.6 ± 7.4 (scale 6-60). The mean "Overall Opinion score" was 2.5 ± 1.8 by patients and 1.9 ± 1.3 by observers (scale 1-10).
Limitations:
This was a single institution study with a small sample size.
Conclusion:
Our study demonstrates that dCHPM allografts are a viable alternative repair option for Mohs surgical defects of the nose.
