Oak toxicosis in cattle in northern California: clinical and pathologic findings

Sixteen calves (3 to 8 months old) affected with oak toxicosis were studied. Clinical, laboratory, and pathologic findings during the peracute through chronic stages were documented. Of the calves studied, 1 died, and 9 others were euthanatized because death was imminent. To evaluate chronic effects, the 6 remaining cattle were euthanatized after 2 months. One calf with acute toxicosis was treated successfully with diuretics and fluid volume replacements containing sodium chloride and calcium. Clinical and laboratory data were compared between survivors and nonsurvivors. A statistically significant (P less than 0.02) difference was found only in serum creatinine concentration at the time of initial reexamination. A decrease in BUN and creatinine values during the next 7 days and the lack of anorexia after the acute phase were the best prognostic indicators for survival.