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Updated: Aug 9, 2025

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Published on: April 18, 2011
Use of Escitalopram for pseudobulbar affect following severe traumatic
Muhammad Faisal Amir Malik1, Mahmood Ali Khan Jafri1, Asad Tamizuddin Nizami1
1Institute of Psychiatry, Rawalpindi Medical University, Rawalpindi,Pakistan.
Abstract:
Those who have suffered from traumatic brain injury (TBI) often develop behavioural, affective, and cognitive complications. Some might experience episodes of involuntary and/or exaggerated laughter and crying. This condition is commonly known as 'pseudobulbar affect'(PBA) and leads to anger, frustration, and social disability. This case report presents the use of low-dose Escitalopram in an individual suffering from agitation and PBA following severe TBI (sTBI). It emphasises the importance of adopting a holistic approach in the treatment of such individuals with appropriate attention paid to factors such as cognitive and behavioural impairment, and caregiver distress.
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