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Published on: October 27, 2014
Recent management trends of subependymal giant cell astrocytoma associated with tuberous sclerosis complex
Zara Shah1, Aimen Tameezuddin2, Muhammad Waqas Saeed Baqai3
1Section of Neurosurgery, Department of Surgery, Aga Khan University Hospital, Karachi.
Abstract:
Subependymal giant cell astrocytomas (SEGA) are benign cranial tumours typically found in patients with tuberous sclerosis complex (TSC). Surgical resection has been the standard treatment for SEGA, however, medical management through mTOR inhibitors has now predominantly replaced surgery as the primary treatment modality. Additionally, newer treatment modalities have emerged with the hopes of providing safer methods for treating the tumour such as laser interstitial thermal therapy (LITT). However, very few reports have addressed these newer methods and analysed the results.

