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The Most rapid recurrent meningioma: Case report and literature review
Novan Krisno Adji1, Komang Yunita Wiryaning Putri2, Laksmi Indreswari3
1Department of Neurosurgery, Soebandi Regional Hospital, Jember, Indonesia; Faculty of Medicine, University of Jember, Indonesia.
Introduction:
Meningioma, a primary intracranial neoplasm, accounts for 36 % of all primary brain tumors. Approximately 90 % of cases are benign. Malignant, atypical and anaplastic meningioma potentially have more recurrence risk. In this paper, we report a rapid recurrence of meningioma that is probably the most rapid recurrence for either benign or malignant type.
Case Presentation:
This paper reports a case of rapid meningioma recurrence 38 days after the first surgical resection. The histopathological examination showed suspicion of anaplastic meningioma (WHO grade III). The patient has a history of breast cancer. After total surgical resection, there was no recurrence reported until three months, and the patient was planned for radiotherapy. Only several cases have been reported about the recurrence of meningioma. With recurrence the prognosis is poor, and two patients died several days after treatment. The primary treatment for the entire tumor was surgical resection, and several issues were combined with radiotherapy. In this case, the recurrence time from the first surgery was 38 days. The most rapid recurrent meningioma reported to this day was 43 days.
Conclusion:
This case report showed the most rapid onset of recurrent meningioma. Therefore this study cannot show reasons for the rapid onset of recurrence.
Insights
This case report details the fastest recorded meningioma recurrence, occurring just 38 days post-surgery. This rapid recurrence highlights the aggressive potential of some meningiomas, even benign types.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Pathology
Background:
- Meningiomas represent 36% of primary brain tumors, with 90% being benign.
- Malignant, atypical, and anaplastic meningiomas carry a higher risk of recurrence.
- Understanding meningioma recurrence patterns is crucial for patient prognosis and treatment strategies.
Observation:
- A case of meningioma recurrence is presented, occurring exceptionally rapidly at 38 days after initial surgical resection.
- Histopathological examination suggested anaplastic meningioma (WHO grade III).
- The patient had a prior history of breast cancer.
Findings:
- This represents the most rapid meningioma recurrence documented to date, surpassing previous records.
- The rapid recurrence occurred despite initial total surgical resection.
- The prognosis for recurrent meningioma is generally poor, with rapid progression observed in some cases.
Implications:
- This case underscores the possibility of extremely rapid meningioma recurrence, challenging current understanding.
- Further research is needed to elucidate the factors contributing to such rapid recurrence.
- Clinical vigilance and prompt re-evaluation are essential for patients with suspected meningioma recurrence.
