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Related Experiment Videos

Multiple use of plasmafilters.

K N Lai1, F M Lai, C W Lam

  • 1Department of Medicine, Prince of Wales Hospital, Chinese University of Hong Kong.

Journal of Clinical Apheresis
|January 1, 1987
PubMed
Summary
This summary is machine-generated.

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Reusing membrane plasmafilters for plasmapheresis is safe and effective. This practice maintains membrane permeability and can significantly reduce treatment costs.

Area of Science:

  • Nephrology
  • Biomedical Engineering
  • Medical Technology

Background:

  • Plasmapheresis is a medical procedure to remove plasma from blood.
  • Plasmafilters are critical components in plasmapheresis.
  • The cost-effectiveness of plasmapheresis can be improved by reusing components.

Purpose of the Study:

  • To evaluate the safety and efficacy of multiple uses of membrane plasmafilters.
  • To assess the impact of plasmafilter reuse on membrane permeability characteristics.
  • To determine the economic benefits of reusing plasmafilters in plasmapheresis.

Main Methods:

  • Six patients undergoing intermittent or regular plasmapheresis were studied.
  • Plasmafilters were cleaned using flushing and ultrafiltration with positive pressure.

Related Experiment Videos

  • Membrane permeability was assessed by measuring clearances and sieving coefficients during 56 treatments with reused filters.

    • Main Results:

    • Clearances for nitrogen urea and creatinine remained consistent.
    • Sieving coefficients for albumin and immunoglobulins were unchanged.
    • No adverse effects related to plasmafilter reuse were observed.

    Conclusions:

    • Multiple uses of membrane plasmafilters are safe and efficient.
    • Plasmafilter reuse does not compromise essential membrane functions.
    • Reusing plasmafilters offers a viable strategy for cost containment in plasmapheresis.