Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mitral Valve Prolapse I: Introduction

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...

Mitral Stenosis I: Introduction

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Owner Obtained Intraocular Pressure Measurements in Canine Primary Angle Closure Glaucoma: A Pilot Study in 14 Dogs.

Veterinary ophthalmology·2026

Same author

Myelolipomas in exotic pets, research, zoo, and wild animals: description of 52 cases and literature review.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2025

Same author

Morphological, Histochemical and Immunohistochemical Characterisation of the Penis in Free-Ranging Giant Anteaters (Myrmecophaga tridactyla).

Anatomia, histologia, embryologia·2025

Same author

A retrospective study of benign epithelial salivary gland neoplasia in 11 dogs and 5 cats.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2025

Same author

Factors Affecting Sleep Among Dogs and Cats in a Veterinary Intensive Care Unit.

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2025

Same author

Serial Evaluation of Pectinate Ligament Morphology Is Not Useful in Predicting the Onset of Intraocular Pressure Elevation in Dogs With Primary Angle Closure Glaucoma.

Veterinary ophthalmology·2025

Search research articles

Related Experiment Video

Updated: Aug 9, 2025

Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty

Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty

Published on: September 17, 2014

Equine pectinate ligament descemetization is associated with age.

Tara M Stonex¹, Tatiane Terumi Negrao Watanabe², James B Robertson¹

¹College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.

Veterinary Ophthalmology

|February 21, 2023

Summary

Equine pectinate ligament descemetization is linked to aging, not glaucoma. This finding suggests it is not a reliable histologic marker for equine glaucoma diagnosis.

Keywords:

equine equine recurrent uveitis glaucoma histopathology iridocorneal angle pectinate ligaments

More Related Videos

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Related Experiment Videos

Last Updated: Aug 9, 2025

Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty

Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty

Published on: September 17, 2014

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Area of Science:

Ophthalmology
Veterinary Pathology
Equine Medicine

Background:

Pectinate ligament descemetization is a condition affecting the equine eye.
Its association with ocular diseases like glaucoma and uveitis requires clarification.
Histologic markers are crucial for accurate diagnosis in veterinary ophthalmology.

Purpose of the Study:

To investigate the correlation between equine pectinate ligament descemetization and ocular disease.
To determine if descemetization is a reliable indicator of glaucoma in horses.

Main Methods:

Retrospective analysis of 66 equine globes (2010-2021).
Evaluation of iridocorneal angles (ICA) for descemetization, angle collapse, and cellular infiltrate.
Disease status (glaucoma, uveitis, other) assigned from clinical records; slides reviewed by two blinded investigators.

Main Results:

Pectinate ligament descemetization was more prevalent in control eyes ('other' ocular disease) than in glaucoma or uveitis groups.
Descemetization length showed a positive correlation with age (13.5 μm increase per year, p=0.016).
Higher infiltrate and angle closure scores were observed in glaucoma and uveitis groups compared to controls (p<0.001).

Conclusions:

Equine pectinate ligament descemetization is associated with increased age.
It should not be considered a reliable histologic marker for equine glaucoma.
Further research may explore other potential causes or implications of descemetization.