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Updated: Aug 9, 2025
A Tandem Liquid Chromatography–Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus
Published on: March 28, 2017
Changes in the Protein Profile in Staphylococcal Strains from Patients Infected with the SARS-CoV-2 Virus
Tomasz Jarzembowski1, Lidia Piechowicz1, Marek Bronk2
1Department of Medical of Microbiology, Medical Faculty, Medical University of Gdansk, Gdansk, Poland.
Abstract:
Staphylococcus aureus strains are particularly often isolated from patients with SARS-CoV-2 infection. The aim of the current research was to determine whether the SARS-CoV-2 virus infection affects the protein profile of S. aureus. Bacteria were isolated from the forty swabs collected from the patients in the hospitals of the Pomeranian region. MALDI-TOF MS spectra were obtained using a Microflex LT instrument. Twenty-nine peaks were identified. The peak (2,430) is described here for the first time and was unique for the isolates from patients infected with the SARS-CoV-2 virus. These results support the hypothesis of bacterial adaptation to the conditions caused by viral infection.
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