Related Experiment Video
Updated: Aug 9, 2025
08:51
Human Egg Maturity Assessment and Its Clinical Application
Published on: August 19, 2019
19.4K
Oocyte in vitro maturation: physiological basis and application to clinical practice
Robert B Gilchrist1, Johan Smitz2
1Fertility & Research Centre, Discipline of Women's Health, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia.
Fertility and Sterility
|February 22, 2023
Summary
Oocyte in vitro maturation (IVM) is a minimally invasive fertility treatment. Recent advances in culture methods and patient protocols have significantly improved IVM success rates, making it a viable option for more patients.
Area of Science:
- Reproductive Medicine
- Assisted Reproductive Technology
Background:
- Oocyte in vitro maturation (IVM) is an assisted reproductive technology.
- Historically, IVM has had a complex history with variable clinical protocols.
- Recent advancements have improved IVM's efficacy and applicability.
Purpose of the Study:
- To review the recent progress and current status of oocyte in vitro maturation (IVM).
- To highlight the improvements in IVM culture methods and patient treatment protocols.
Main Methods:
- Review of recent scientific insights and animal studies related to IVM.
- Analysis of advancements in in vitro culture techniques for oocytes.
- Evaluation of simplified patient treatment protocols for IVM.
Main Results:
- Significant progress has been made in IVM culture methods.
- Simplified patient protocols have enhanced IVM practice.
- IVM is now considered nonexperimental and routinely practiced in specialized centers.
Conclusions:
- IVM is a valuable and increasingly reliable assisted reproductive technology.
- IVM is particularly indicated for patients with polycystic ovaries/syndrome and for fertility preservation in cancer patients.
- Continued advancements position IVM as a key option in reproductive medicine.
