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No bladder irrigation versus continuous bladder irrigation after HoLEP: a propensity score matching analysis
Yunwu Hao1,2, Degang Chen2, Xudong Shen1,3,4
1Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China.
BMC Urology
|February 22, 2023
Summary
A study found that not using bladder irrigation after holmium laser enucleation of the prostate (HoLEP) for benign prostatic hyperplasia (BPH) is safe and effective for selected patients. This approach demonstrated comparable outcomes to continuous irrigation, simplifying post-operative care.
Area of Science:
- Urology
- Surgical Innovation
- Patient Outcomes
Background:
- Benign prostatic hyperplasia (BPH) is a common condition requiring effective treatment.
- Transurethral holmium laser enucleation of the prostate (HoLEP) is a standard surgical option for BPH.
- Post-operative bladder irrigation is a common practice after HoLEP, but its necessity is debated.
Purpose of the Study:
- To evaluate the feasibility and safety of a no bladder irrigation strategy following HoLEP for BPH.
- To compare clinical outcomes and complications between patients with and without post-HoLEP bladder irrigation.
Main Methods:
- A retrospective study comparing 62 patients who did not receive bladder irrigation (Group A) with 150 patients who did (Group B) after HoLEP.
- Propensity score matching (PSM) was used to ensure baseline comparability between groups.
- Key outcome measures included pre- and post-operative International Prostate Symptom Score (IPSS), Quality of Life (QOL), maximum urinary flow rate (Qmax), postvoid residual urine (PVR), and complication rates.
Main Results:
- PSM successfully matched 47 pairs of patients, showing no significant differences in intraoperative conditions or early post-operative complications.
- Both groups showed significant improvements in IPSS, QOL, Qmax, and PVR one month after surgery.
- No statistically significant differences in IPSS, QOL, Qmax, PVR, or early complications were observed between the groups within one month post-surgery.
Conclusions:
- The no bladder irrigation strategy after HoLEP for BPH is a safe and effective option for carefully selected patients.
- This approach can potentially streamline post-operative care without compromising patient outcomes.
- Further research may support wider adoption of this simplified post-operative regimen.

