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Factors Related to Quality of Life in Children With Cerebral Palsy

Montse Blasco1, María García-Galant1, Olga Laporta-Hoyos1

  • 1Departament de Psicologia Clínica i Psicobiologia, Universitat de Barcelona, Barcelona, Spain; Institut de Neurociències, Universitat de Barcelona, Barcelona, Spain; Institut de Recerca Sant Joan de Déu, Barcelona, Spain.

Pediatric Neurology
|February 22, 2023
PubMed

Insights

Executive functioning and motor status significantly impact the quality of life (QOL) for children with cerebral palsy (CP). Cognitive interventions may enhance QOL in these children.

Area of Science:

  • Pediatrics
  • Neuroscience
  • Rehabilitation Medicine

Background:

  • Cerebral palsy (CP) significantly affects children's quality of life (QOL).
  • Understanding factors influencing QOL is crucial for targeted interventions.
  • Proxy-reported QOL is a key outcome measure in pediatric CP research.

Purpose of the Study:

  • To investigate demographic, clinical, neuropsychological, and psychosocial predictors of QOL in children with CP.
  • To identify specific variables associated with different QOL domains.
  • To inform potential therapeutic targets for improving QOL in pediatric CP.

Main Methods:

  • Utilized the proxy-reported Cerebral Palsy Quality of Life-Child questionnaire (CP QOL-Child) in 58 children with CP.
  • Assessed relationships between QOL scores and various demographic, clinical, neuropsychological, and psychosocial variables.
  • Employed multiple linear regression analysis to identify significant explanatory variables for QOL.

Main Results:

  • Executive functioning and motor status were significant predictors of overall QOL.
  • Executive functions explained variance in Social Wellbeing, Feelings about Functioning, and Emotional Wellbeing domains.
  • Parental stress, visual perception, and autism spectrum disorder (ASD) traits were associated with specific QOL domains.

Conclusions:

  • Executive functioning and motor status are critical determinants of QOL in children with CP.
  • Cognitive function interventions show promise for enhancing QOL.
  • Addressing factors like parental stress and visual perception may improve specific QOL aspects.
Abstract

Keywords:
Cerebral palsyChildrenExecutive functionsQuality of life

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