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Relationship between sexual and bladder dysfunction in women consuming ketamine
Bor-En Jong1, Shang-Jen Chang1,2, Chia-Hua Li3
1Division of Urology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan.
The Journal of Sexual Medicine
|February 22, 2023
Summary
Female ketamine abusers experiencing lower urinary tract symptoms (LUTS) are more likely to have female sexual dysfunction (FSD). This highlights the importance of addressing LUTS in this population.
Area of Science:
- Urology
- Psychiatry
- Pharmacology
Background:
- Ketamine abuse is prevalent, yet research on female sexual dysfunction (FSD) in ketamine abusers (KAs) is scarce.
- This study addresses the under-investigated area of FSD in women misusing ketamine.
Purpose of the Study:
- To compare FSD and lower urinary tract symptoms (LUTS) between street and hospital-based KAs.
- To identify risk factors associated with FSD and LUTS in KAs.
Main Methods:
- A cross-sectional study involving 139 female KAs (aged ≥18) who completed anonymous questionnaires.
- Data collected on drug use history, FSD symptoms, and LUTS severity using validated scales (ICSI, ICPI, BSRS-5).
Main Results:
- FSD was reported by 76% of participants; 97% of hospital KAs vs. 68% of street KAs experienced FSD (P < 0.001).
- LUTS were significantly more prevalent in hospital KAs (71%) than street KAs (8%) (P < 0.001).
- LUTS, longer ketamine use (≥36 months), and psychological symptoms (BSRS-5 ≥6) were significant risk factors for FSD and LUTS.
Conclusions:
- Female ketamine abusers with LUTS are significantly more likely to experience FSD.
- Sexual health issues in KAs, particularly those with LUTS, warrant clinical attention.
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