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Prevalence and Risk Factors of Frailty in Stroke Patients: A Meta-Analysis and Systematic Review
1Yuxia Ma, Lin Han, Lanzhou University, China Email: yuxiama@lzu.edu.cn,
The Journal of Nutrition, Health & Aging
|February 22, 2023
Summary
Frailty affects 27% of stroke patients, with higher prevalence in women and older individuals. Key risk factors include diabetes, hyperlipidemia, and atrial fibrillation, necessitating early screening.
Area of Science:
- Gerontology
- Neurology
- Public Health
Background:
- Frailty is a significant concern in stroke recovery, impacting patient outcomes.
- Existing evidence on frailty prevalence and risk factors in stroke survivors requires synthesis.
Approach:
- A comprehensive systematic review and meta-analysis was conducted.
- Data from 24 studies involving 30,423 stroke patients were analyzed.
- Studies were assessed for quality using established methodologies.
Key Points:
- The prevalence of frailty and pre-frailty in stroke patients was found to be 27% and 47.9%, respectively.
- Identified risk factors for frailty include female gender, advanced age, diabetes, hyperlipidemia, atrial fibrillation, and higher National Institutes of Stroke Scale (NIHSS) admission scores.
- These findings highlight specific demographic and clinical characteristics associated with increased frailty risk.
Conclusions:
- Frailty is highly prevalent among stroke patients.
- Early identification and intervention for frailty in high-risk stroke populations are crucial.
- Further research and clinical attention should focus on preventing and managing frailty in stroke survivors.

