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Updated: Aug 9, 2025

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Mapping Genome-wide Accessible Chromatin in Primary Human T Lymphocytes by ATAC-Seq
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ATAC-See: A Tn5 Transposase-Mediated Assay for Detection of Chromatin Accessibility with Imaging
Yonglong Dang1, Ram Prakash Yadav1, Xingqi Chen2
1Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Methods in Molecular Biology (Clifton, N.J.)
|February 22, 2023
Abstract:
Assay of transposase-accessible chromatin with visualization (ATAC-see), a transposase-mediated imaging technology that enables direct imaging of the accessible genome in situ and deep sequencing to reveal the identity of the imaged elements. Here we image spatial organization of the accessible genome in HT1080 cells with this method.

