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Reduced Pain and Improved Function Following Short-Term Use of Noninvasive BioWave High Frequency Peripheral Nerve
Alaa Abd-Elsayed1, Michael Gyorfi2, Michael Fischman3
1Department of Anesthesiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, B6/319 CSC, Madison, WI, 53792-3272, USA. alaaawny@hotmail.com.
Pain and Therapy
|February 22, 2023
Summary
Noninvasive neuromodulation significantly reduced chronic pain by 46% in 1511 patients over two weeks. This safe and effective therapy also improved daily function and decreased medication reliance.
Area of Science:
- Neurology
- Pain Management
- Biomedical Engineering
Background:
- Peripheral nervous system targets chronic pain therapies.
- Noninvasive neuromodulation offers a safer alternative for pain relief.
- This study investigates a noninvasive neuromodulation system over a 2-week period.
Purpose of the Study:
- Evaluate the efficacy of noninvasive neuromodulation for chronic pain.
- Assess improvements in pain scores and functional metrics.
- Determine patient satisfaction and medication usage changes.
Main Methods:
- Retrospective, open-label survey of 1511 chronic pain patients.
- Patients used a noninvasive neuromodulation system for 2 weeks.
- Assessed pain scores, functional metrics (mood, sleep, mobility), ADL, and medication use.
Main Results:
- Overall pain reduction of 46% observed.
- Significant improvements in mood and sleep (over 47%).
- 42% of patients reduced or eliminated medication; no adverse events reported.
Conclusions:
- Noninvasive neuromodulation shows significant pain reduction and functional improvement within 2 weeks.
- It is a promising, safe, and cost-effective therapy for chronic pain.
- Future research should include long-term follow-up and placebo-controlled trials.

