Related Experiment Video

Updated: Aug 9, 2025

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

14.2K

Long-term visual acuity outcome of pediatric uveitis patients presenting with severe visual impairment

Usanee Tungsattayathitthan1, Narisa Rattanalert1, Wantanee Sittivarakul2

  • 1Department of Ophthalmology, Faculty of Medicine, Prince of Songkla University, 15 Karnjanavanich Road, Hat Yai, 90110, Songkhla, Thailand.

Scientific Reports
|February 22, 2023
PubMed

Insights

Children with severe visual impairment from uveitis often have poor long-term vision outcomes. Early diagnosis and treatment are crucial for better visual acuity (VA) in pediatric uveitis cases.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Immunology

Background:

  • Uveitis in children can lead to severe visual impairment (SVI).
  • Long-term visual acuity (VA) outcomes for pediatric uveitis with SVI at presentation are not well-established.
  • Understanding predictive factors for VA outcomes is crucial for management.

Purpose of the Study:

  • To investigate the long-term visual acuity (VA) outcome in children with uveitis and severe visual impairment (SVI) at presentation.
  • To identify factors associated with VA improvement or decline over time.

Main Methods:

  • Retrospective review of 57 eyes of 51 children (≤16 years) with uveitis and SVI (VA ≤ 20/200) managed between 2010-2020.
  • Analysis of clinical data, including uveitis type, diagnosis, complications, and VA measurements at presentation and follow-up.
  • Statistical analysis to identify predictive factors for VA outcomes.

Main Results:

  • The mean logMAR VA improved from 1.8 at presentation to 1.2 at 5 years (P < 0.001).
  • Ocular complications were present in 93% of eyes at presentation.
  • Factors predicting poorer VA outcome included preschool age of onset, delayed diagnosis (≥1 month symptom duration), and non-anterior uveitis.

Conclusions:

  • Long-term visual acuity outcomes for pediatric uveitis with SVI at presentation are generally unfavorable.
  • Younger age at onset, delayed presentation, and posterior segment involvement are associated with poorer visual outcomes.
  • Aggressive management and early intervention are critical for improving visual prognosis in pediatric uveitis.

More Related Videos

Stereoacuity Improvement using Random-Dot Video Games06:25

Stereoacuity Improvement using Random-Dot Video Games

Published on: January 14, 2020

14.5K
The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish04:56

The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish

Published on: October 9, 2013

20.6K

Related Concept Videos

Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.2K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
514
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
602
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
670