Related Experiment Video
Updated: Aug 9, 2025

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting
Published on: March 9, 2017
Aggregation-Induced Electrochemiluminescence and Nitric Oxide Recognition by Halogen Bonding with a Ruthenium(II)
Yafang Gao1, Linlin Zhang1, Ziqi Wang1
1Key Laboratory of Beijing on Regional Air Pollution Control Department of Environmental Science, Beijing University of Technology, No.100 pingleyuan, Beijing, China.
Abstract:
In this study, a new strategy for NO detection based on the aggregation-induced electrochemical luminescence (AIECL) of a ruthenium-based complex and the halogen bonding effect was developed. First, [Ru(phen)2 (phen-Br2 )]2+ (phen : 1,10-phenanthroline, phen-Br2 : 3,8-dibromo-1,10-phenanthroline) was synthesized and exhibited aggregation-induced emission (AIE) and AIECL properties in a poor solvent (H2 O). [Ru(phen)2 (phen-Br2 )]2+ exhibited greatly enhanced AIECL properties compared to its AIE intensity. When the volume fraction of water (fw , v %) in the H2 O-acetonitrile (MeCN) system was increased from 30 to 90 %, the photoluminescence and electrochemiluminescence (ECL) intensities were three- and 800-fold that of the pure MeCN system, respectively. Dynamic light scattering and scanning electron microscopy results indicated that [Ru(phen)2 (phen-Br2 )]2+ aggregated into nanoparticles. AIECL is sensitive to NO because of its halogen bonding effect. The C-Br⋅⋅⋅N bond between [Ru(phen)2 (phen-Br2 )]2+ and NO increased the distance of complex molecules, resulting in ECL quenching. A detection limit of 2 nM was obtained with 5 orders of magnitude linear range. The combination of the AIECL system and the halogen bond effect expands the theoretical research and applications in biomolecular detection, molecular sensors, and stages of medical diagnosis.
More Related Videos
Related Concept Videos
Metal-Ligand Bonds
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
Photoluminescence: Applications
Complexation Equilibria: The Chelate Effect
Valence Bond Theory
Coordination Compounds and Nomenclature
1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Mechanism

