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Updated: Aug 9, 2025

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
Small lymphocytic lymphoma presenting as chronic diffuse lip swelling
Jennifer E Yeh, Mayra E Lorenzo, Cecilia Larocca
1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. rkforeman@partners.org,jeyeh@stanford.edu.
Abstract:
Although rare, small lymphocytic lymphoma can present as chronic lip swelling and papules, thus mimicking the features of orofacial granulomatosis, a chronic inflammatory disorder characterized by subepithelial noncaseating granulomas, or papular mucinosis, characterized by localized dermal mucin deposition of mucin. When assessing lip swelling, one must carefully consider the clinical clues and have a low threshold to perform a diagnostic tissue biopsy, preventing delays in treatment or progression of the lymphoma.

