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Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
14:04

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria

Published on: May 8, 2013

Drug resistance and pathogenicity of S. aureus isolated from patients

F Výmola1, N A Semina, K K Gladkova

  • 1Institute of Hygiene and Epidemiology, Prague, Czechoslovakia.

Journal of Hygiene, Epidemiology, Microbiology, and Immunology
|January 1, 1987
PubMed

Insights

This study examined antibiotic resistance in Staphylococcus aureus strains from clinical settings. Most strains showed multiple drug resistance, but no link was found between resistance and toxin production.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Epidemiology

Background:

  • Staphylococcus aureus is a significant pathogen in both hospital and community settings.
  • Understanding antimicrobial resistance patterns is crucial for effective treatment strategies.
  • Previous research has explored S. aureus resistance, but specific correlations with enterotoxigenicity require further investigation.

Purpose of the Study:

  • To investigate the prevalence of antibiotic resistance in clinical S. aureus isolates.
  • To determine the relationship between antimicrobial drug resistance and enterotoxigenic properties.
  • To analyze phage group specificity in relation to drug resistance.

Main Methods:

  • A joint study was conducted between the Institute of Hygiene and Epidemiology, Prague, and the Central Research Institute of Epidemiology, Moscow.
  • A total of 277 S. aureus strains were randomly isolated from infant and adult inpatients between 1983-1985.
  • Antimicrobial resistance profiles, enterotoxigenic properties, and phage group specificity were assessed.

Main Results:

  • The majority of S. aureus strains exhibited multiple drug resistance.
  • High rates of resistance were observed for Penicillin (PNC, 77.9%), Chloramphenicol (CMP, 52.7%), Tetracycline (TET, 21.6%), Erythromycin (ERY, 17.6%), and Lincomycin (LIN, 11.9%).
  • Strains isolated from infants showed a higher frequency of resistance to Tetracycline and Erythromycin. No correlation was found between antimicrobial resistance and the toxigenic properties of the strains.

Conclusions:

  • Multiple antibiotic resistance is prevalent in clinical S. aureus isolates.
  • Infant isolates demonstrated a notable resistance pattern to Tetracycline and Erythromycin.
  • Antimicrobial resistance in S. aureus strains was not associated with their enterotoxigenic potential in this study.

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