Vibrational coupling with O-H stretching increases catalytic efficiency of sucrase in Fabry-Pérot microcavity
Jiaqi Bai1, Zixin Wang2, Chengjian Zhong1
1The School of Biomedical Engineering, Guangzhou Medical University, Xinzao Town, Panyu District, Guangzhou, 511436, China.
Abstract:
Vibrational strong coupling (VSC) has been reported as a polariton-based method for modulating the rate of biochemical reactions. Herein, we studied how VSC modulates the sucrose hydrolysis. By monitoring the refractive index-induced shift of Fabry-Pérot microcavity, in which the catalytic efficiency of sucrose hydrolysis can be increased at least two times, as VSC was tuned to resonate with the stretching vibration of O-H bonds. This research provides new evidence for applying VSC in life sciences, which holds great promise to improving enzymatic industries.
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