Related Experiment Video

Updated: Aug 9, 2025

Subconjunctival Administration of Adeno-associated Virus Vectors in Small Animal Models
06:16

Subconjunctival Administration of Adeno-associated Virus Vectors in Small Animal Models

Published on: March 16, 2022

3.0K

Case for conservative management of adenoviral pseudomembranous conjunctivitis

Kenneth McNair Gilmour1, Kanna Ramaesh2

  • 1Ophthalmology, Tennent Institute of Ophthalmology, Glasgow, UK kenneth.gilmour2@nhs.scot.

BMJ Case Reports
|February 22, 2023
PubMed

Insights

Severe adenoviral pseudomembranous conjunctivitis can cause lasting eye damage. Conservative management with lubricants and corticosteroids, avoiding debridement, proved effective in two cases.

Area of Science:

  • Ophthalmology
  • Virology

Background:

  • Adenoviral pseudomembranous conjunctivitis is typically self-limiting but can cause severe inflammation.
  • Severe cases may lead to subepithelial infiltrates, pseudomembranes, and symblepharon.
  • Optimal management strategies, including debridement, lack robust evidence.

Observation:

  • Two cases of PCR-proven adenoviral pseudomembranous conjunctivitis were analyzed.
  • Patients presented with severe inflammatory responses.
  • Conservative management was chosen over debridement.

Findings:

  • Conservative treatment with topical lubricants and corticosteroids was effective.
  • This approach avoided surgical intervention.
  • Positive clinical outcomes were achieved without debridement.

Implications:

  • Conservative management may be a viable alternative to debridement for severe cases.
  • This approach could prevent long-term sequelae associated with aggressive interventions.
  • Further research is warranted to establish evidence-based guidelines for managing this condition.
Keywords:
Anterior chamberVisual pathway

More Related Videos

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits07:43

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits

Published on: January 8, 2020

10.2K
Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity05:46

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity

Published on: September 20, 2024

494

Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
602
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
514
Tonsillitis II: Management01:26

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
154
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
670
Direct-Acting Cholinergic Agonists: Therapeutic Uses01:11

Direct-Acting Cholinergic Agonists: Therapeutic Uses

Direct-acting cholinergic agonists have many therapeutic uses in various medical fields. Choline esters, including acetylcholine, have limited clinical utility due to their non-selectivity and short duration of action. Still, acetylcholine and carbachol are applied topically during ophthalmologic surgery to induce miosis. Pilocarpine, a muscarinic and ganglionic stimulator, effectively treats open-angle glaucoma and alleviates xerostomia and dry mouth caused by radiotherapy or Sjögren...
817