Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

20
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
20
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

16
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
16
Clinical Trials: Overview01:11

Clinical Trials: Overview

3.1K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
3.1K
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

31
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
31
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

17
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
17

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vendor-independent Aortic Valve Calcium Scoring in Patients with Discordant Echocardiographic Criteria of Severe Aortic Stenosis.

Radiology. Cardiothoracic imaging·2026
Same author

Vascular Endothelial Function, Carotid Intima-Media Thickness and Coronary Artery Calcification in Women.

Journal of clinical medicine·2026
Same author

Primary Results of the SALAMANDER Registry: A Multicenter Observational Cohort Study.

Journal of the American Heart Association·2026
Same author

Detection of Biventricular Volume Increase in Overweight and Obese Individuals Using a Novel Index of the "Standard Human"-A Single-Center, Non-Contrast-Enhanced Cardiac CT Study.

Journal of clinical medicine·2026
Same author

Mortality score in chronic coronary syndrome: prediction model from the ISCHEMIA trial.

European journal of preventive cardiology·2026
Same author

Percutaneous Closure of a Large-Bore Carotid Arteriotomy Using a Collagen-Based Vascular Plug.

Life (Basel, Switzerland)·2026

Related Experiment Video

Updated: Aug 9, 2025

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
04:30

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

25.6K

Drug-Eluting Stents: Technical and Clinical Progress.

Maciej Koźlik1, Jan Harpula1, Piotr J Chuchra2

  • 1Division of Cardiology and Structural Heart Disease, Medical University of Silesia, 40-635 Katowice, Poland.

Biomimetics (Basel, Switzerland)
|February 22, 2023
PubMed
Summary

Drug-eluting stents (DES) offer superior outcomes in percutaneous revascularization. This review examines how stent material, strut design, and coating impact cardiovascular outcomes for DES.

Keywords:
coating techniquedrugdrug-eluting stentsoverexpansionpolymerscaffold

More Related Videos

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents
06:55

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents

Published on: October 26, 2016

9.0K
Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers
12:30

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers

Published on: August 12, 2014

9.9K

Related Experiment Videos

Last Updated: Aug 9, 2025

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
04:30

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

25.6K
Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents
06:55

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents

Published on: October 26, 2016

9.0K
Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers
12:30

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers

Published on: August 12, 2014

9.9K

Area of Science:

  • Cardiovascular Medicine
  • Biomedical Engineering
  • Interventional Cardiology

Background:

  • Drug-eluting stents (DES) are the standard for percutaneous revascularization due to superior efficacy over bare metal stents and balloon angioplasty.
  • Continuous innovation in DES technology focuses on enhancing efficacy and safety through material science, design, and drug delivery.

Purpose of the Study:

  • To review the current landscape of coronary stents.
  • To analyze the impact of stent material, strut design, and coating techniques on cardiovascular outcomes.
  • To provide insights into subtle differences between DES platforms and their clinical implications.

Main Methods:

  • Literature review of current coronary stent technologies.
  • Analysis of studies evaluating the influence of stent platform characteristics on clinical outcomes.
  • Synthesis of data on materials, strut designs, and coating methods in DES.

Main Results:

  • DES significantly outperform older revascularization methods.
  • Advancements in stent materials, strut configurations, and polymer coatings are key to improved DES performance.
  • Variations in stent design can lead to significant differences in clinical results.

Conclusions:

  • Understanding the nuances of DES design is critical for optimizing patient outcomes.
  • Ongoing research and development in stent technology are essential for advancing cardiovascular care.
  • The choice of DES platform, considering its material, design, and coating, directly influences cardiovascular outcomes.