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Updated: Aug 9, 2025

3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography
Published on: October 24, 2019
Evaluation of thin-slice abdominal DECT using deep-learning image reconstruction in 74 keV virtual monoenergetic
Jack J Xu1,2, Lars Lönn3,4, Esben Budtz-Jørgensen5
1Department of Diagnostic Radiology, Copenhagen University Hospital, Rigshospitalet, 2100, Copenhagen, Denmark. jack.junchi.xu@regionh.dk.
Purpose:
To compare noise, contrast-to-noise ratio (CNR), signal-to-noise ratio (SNR) and image quality using deep-learning image reconstruction (DLIR) vs. adaptive statistical iterative reconstruction (ASIR-V) in 0.625 and 2.5 mm slice thickness gray scale 74 keV virtual monoenergetic (VM) abdominal dual-energy CT (DECT).
Methods:
This retrospective study was approved by the institutional review board and regional ethics committee. We analysed 30 portal-venous phase abdominal fast kV-switching DECT (80/140kVp) scans. Data were reconstructed to ASIR-V 60% and DLIR-High at 74 keV in 0.625 and 2.5 mm slice thickness. Quantitative HU and noise assessment were measured within liver, aorta, adipose tissue and muscle. Two board-certified radiologists evaluated image noise, sharpness, texture and overall quality based on a five-point Likert scale.
Results:
DLIR significantly reduced image noise and increased CNR as well as SNR compared to ASIR-V, when slice thickness was maintained (p < 0.001). Slightly higher noise of 5.5-16.2% was measured (p < 0.01) in liver, aorta and muscle tissue at 0.625 mm DLIR compared to 2.5 mm ASIR-V, while noise in adipose tissue was 4.3% lower with 0.625 mm DLIR compared to 2.5 mm ASIR-V (p = 0.08). Qualitative assessments demonstrated significantly improved image quality for DLIR particularly in 0.625 mm images.
Conclusions:
DLIR significantly reduced image noise, increased CNR and SNR and improved image quality in 0.625 mm slice images, when compared to ASIR-V. DLIR may facilitate thinner image slice reconstructions for routine contrast-enhanced abdominal DECT.
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