Introduction to interventional oncology: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper

Area of Science:

• Pediatric Oncology
• Interventional Radiology
• Minimally Invasive Procedures

Background:

• Interventional radiology (IR) plays an increasingly vital role in managing pediatric solid tumors.
• Minimally invasive, image-guided procedures are essential for diagnosis and therapy in pediatric oncology.
• IR is becoming an integral part of the multidisciplinary oncology team.

Purpose of the Study:

• To highlight the contributions of interventional radiology in pediatric solid tumor care.
• To emphasize the diagnostic and therapeutic applications of IR in pediatric oncology.
• To showcase the supportive procedures IR offers to oncology patients.

Main Methods:

• Utilizing advanced imaging for precise biopsy guidance.
• Employing transarterial locoregional treatments for targeted chemotherapy delivery.
• Performing percutaneous thermal ablation for chemo-resistant tumors.
• Conducting routine supportive procedures like central venous access, lumbar punctures, and feeding tube placement.

Main Results:

• Improved visualization during diagnostic biopsies.
• Effective targeted delivery of cytotoxic therapy with reduced systemic side effects.
• Successful treatment of solid organ tumors resistant to chemotherapy.
• High technical success and safety profiles for supportive procedures.

Conclusions:

• Interventional radiology is a valuable resource for pediatric solid tumor patients.
• IR procedures offer effective diagnostic and therapeutic options.
• IR significantly contributes to supportive care, enhancing patient management and outcomes.