Related Experiment Video

Updated: Aug 9, 2025

Iatrogenic Injury Recapitulated: Electroexcision Technique for Urethral Stricture Modeling in Rats
03:37

Iatrogenic Injury Recapitulated: Electroexcision Technique for Urethral Stricture Modeling in Rats

Published on: October 11, 2024

418

Retraction

    Journal of Cellular Physiology
    |February 22, 2023
    PubMed

    Insights

    This study on papillary thyroid carcinoma is retracted due to unverified experimental data and image inconsistencies. The authors and journal agreed the findings are invalid.

    Area of Science:

    • Oncology
    • Molecular Biology
    • Genetics

    Context:

    • Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer.
    • The epithelial-mesenchymal transition (EMT) plays a critical role in tumor progression and metastasis in PTC.
    • Long noncoding RNAs (lncRNAs) are increasingly recognized as key regulators in cancer development.

    Purpose:

    • To investigate the role of long noncoding RNA SLC26A4-AS1 in papillary thyroid carcinoma.
    • To determine the effect of SLC26A4-AS1 overexpression on the epithelial-mesenchymal transition (EMT) process.
    • To elucidate the involvement of the MAPK pathway in the regulation of EMT by SLC26A4-AS1 in PTC.

    Summary:

    • The article investigated the overexpression of long noncoding RNA SLC26A4-AS1 and its inhibitory effect on EMT in papillary thyroid carcinoma via the MAPK pathway.
    • The study aimed to provide insights into the molecular mechanisms underlying PTC progression.
    • The findings were intended to highlight SLC26A4-AS1 as a potential therapeutic target.

    Impact:

    • The article has been retracted due to unverified experimental data and image inconsistencies.
    • The authors, journal editor, and publisher mutually agreed to retract the publication.
    • The conclusions presented in the original article are considered invalid by the editors.

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