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The Pancreas in Coronavirus Disease 2019 Infection
Tiago Correia de Sá1, Mónica Rocha2
1General Surgery Department, Centro Hospitalar do Tâmega e Sousa, Avenida do Hospital Padre Américo 210, 4564-007 Penafiel, Portugal.
Gastroenterology Clinics of North America
|February 22, 2023
Summary
The link between coronavirus disease 2019 (COVID-19) and acute pancreatitis (AP) is unclear. This study analyzes severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pancreatic injury mechanisms and COVID-19
Area of Science:
- Gastroenterology and Hepatology
- Infectious Diseases
- Oncology
Background:
- The association between coronavirus disease 2019 (COVID-19) and acute pancreatitis (AP) is suggested, but underlying mechanisms remain unclear.
- Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) may cause pancreatic injury.
- COVID-19 has presented significant challenges in managing pancreatic cancer.
Purpose of the Study:
- To analyze the mechanisms of pancreatic injury induced by SARS-CoV-2.
- To review existing case reports of AP in COVID-19 patients.
- To examine the impact of the COVID-19 pandemic on pancreatic cancer diagnosis and management.
Main Methods:
- Literature review of SARS-CoV-2 mechanisms for pancreatic injury.
- Systematic review of published case reports linking COVID-19 and AP.
- Analysis of the effects of the pandemic on pancreatic cancer care, including surgical interventions.
Main Results:
- Mechanisms of SARS-CoV-2-induced pancreatic injury are not fully elucidated.
- Case reports indicate a potential link between COVID-19 and AP.
- The pandemic has disrupted standard protocols for pancreatic cancer diagnosis and treatment.
Conclusions:
- Further research is needed to understand SARS-CoV-2's role in AP development.
- COVID-19 poses a complex challenge to pancreatic disease management.
- The pandemic's long-term effects on pancreatic cancer outcomes require ongoing investigation.
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