Related Experiment Video
Updated: Aug 9, 2025
07:54
Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
19.9K
Obstructive Sleep Apnea and Colorectal Cancer: A Systematic Review and Meta-Analysis
Navin Niranjan1, Krishna Bajee Sriram2,3, Vinod Gopalan3
1Department of Respiratory Medicine, Gold Coast University Hospital, 1 Hospital Blvd, Southport, QLD, 4215, Australia. navin.niranjan@health.qld.gov.au.
Journal of Gastrointestinal Cancer
|February 22, 2023
Summary
This meta-analysis found no conclusive evidence that obstructive sleep apnea (OSA) increases colorectal cancer (CRC) risk, though biological links exist. Further research is needed to clarify the OSA-CRC relationship and treatment impacts.
Area of Science:
- Sleep Medicine
- Oncology
- Epidemiology
Background:
- Obstructive sleep apnea (OSA) involves airway collapse, intermittent hypoxia, and sleep fragmentation, with preclinical links to carcinogenesis.
- The clinical association between OSA and colorectal cancer (CRC) remains controversial and requires further investigation.
Conclusions:
- Current evidence is insufficient to establish OSA as a definitive risk factor for CRC development.
- Further well-designed prospective studies and randomized controlled trials are necessary to evaluate CRC risk in OSA patients and the impact of OSA treatment.
More Related Videos
Related Concept Videos
01:21Sleep Apnea
207
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
207
01:17Other Pulmonary Disorders
885
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
885
01:21Barrett Esophagus-II: Clinical Manifestations and Management
246
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
246
02:59Cancer Prevention
6.2K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.2K
01:24Substance Use Disorders Affecting Sleep
205
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
205
01:22Chronic Obstructive Pulmonary Disease
1.4K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.4K