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Symptomatic esophageal intramural pseudodiverticulosis without stricture: A case report
Spiro Veria1, Logan D Glosser1, Conner V Lombardi1
1College of Medicine and Life Sciences, The University of Toledo, Toledo, OH, USA.
Esophageal intramural pseudodiverticulosis, a rare condition, presents challenges in diagnosis and management. This case highlights its co-occurrence with jackhammer esophagus and candidiasis, complicating treatment for dysphagia.
Area of Science:
- Gastroenterology
- Digestive Diseases
- Esophageal Disorders
Background:
- Esophageal intramural pseudodiverticulosis (EIP) is a rare benign condition characterized by esophageal epithelial outpouchings, with fewer than 300 reported cases globally.
- The exact etiology of EIP remains unclear, but risk factors include diabetes mellitus, GERD, candidiasis, and substance abuse.
- EIP typically presents with characteristic endoscopic findings, though treatment options are historically limited to symptom management.
Observation:
- A 52-year-old female with a history of esophageal stricture repairs and dilation presented with persistent dysphagia and food impaction.
- Diagnostic esophagogastroduodenoscopy revealed esophageal intramural pseudodiverticulosis.
- The patient also exhibited concomitant jackhammer esophagus and esophageal candidiasis.
Findings:
- The case demonstrates a rare instance of esophageal intramural pseudodiverticulosis.
- The findings underscore the association of EIP with other esophageal motility disorders and infections.
- This presentation complicated the management of the patient's dysphagia and food impaction.
Implications:
- This case expands the understanding of EIP's clinical presentation and associations.
- It suggests that patients with refractory dysphagia and strictures should be evaluated for EIP and related conditions.
- Further research into the pathogenesis and optimal management strategies for EIP, especially in complex cases, is warranted.
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