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Related Experiment Videos

Altitude and birth weight.

R Yip1

  • 1Division of Nutrition, Centers for Disease Control, Atlanta, GA 30333.

The Journal of Pediatrics
|December 1, 1987
PubMed
Summary
This summary is machine-generated.

High altitude significantly reduces birth weight and increases the risk of low birth weight (LBW) in newborns. This effect is observed across different altitudes, impacting fetal growth and requiring altitude-specific risk assessments.

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Area of Science:

  • Environmental Health
  • Perinatal Epidemiology
  • Public Health

Background:

  • Birth weight is a critical indicator of neonatal health.
  • Altitude is a potential environmental factor influencing birth outcomes.
  • Previous studies suggest a link between high altitude and adverse birth weights.

Purpose of the Study:

  • To investigate the relationship between maternal altitude and birth weight in the U.S.
  • To quantify the effect of increasing altitude on low birth weight (LBW) rates.
  • To identify altitude-specific risk factors for LBW.

Main Methods:

  • Analysis of U.S. natality records (1978-1981).
  • Correlation of birth weights with mean county altitude.
  • Controlled socioeconomic factors by selecting an idealized subpopulation of singleton births.

Related Experiment Videos

  • Examined LBW rates across 500m altitude gradations.

    • Main Results:

    • A significant curvilinear dose-response relationship between increasing altitude and reduced birth weight (P < 0.001).
    • Neonates born above 2000m had a 2-3 fold increase in LBW rate compared to sea level.
    • Higher incidence of intrauterine growth retardation observed at higher altitudes.
    • Positive correlation between LBW rate and high altitude in mountain states.

    Conclusions:

    • Altitude has a general, negative effect on birth weight, independent of socioeconomic factors.
    • Higher altitudes are associated with increased rates of low birth weight, primarily due to intrauterine growth retardation.
    • Altitude-specific LBW cutoff limits can help identify high-risk areas.