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In vitro to in vivo acetaminophen hepatotoxicity extrapolation using classical schemes, pharmacodynamic models and a

Jules Dichamp1,2,3, Geraldine Cellière1, Ahmed Ghallab2,4

  • 1Group SIMBIOTX, INRIA Saclay-Île-de-France, Palaiseau, France.

Frontiers in Bioengineering and Biotechnology
|February 23, 2023
PubMed

Keywords:
APAPacetaminophendigital twindrug toxicityin vitro to in vivo extrapolationmetabolismmodelingmulti-scale

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