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Rising Burden of Psychiatric and Behavioral Disorders and Their Adverse Impact on Health Care Expenditure in
Aravind Thavamani1, Jasmine Khatana2, Krishna Kishore Umapathi3
1Division of Pediatric Gastroenterology, Hepatology and Nutrition, UH Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Insights
The prevalence of psychiatric disorders in hospitalized pediatric inflammatory bowel disease (IBD) patients is rising. These conditions independently increase hospital stays and costs for IBD care.
Area of Science:
- Pediatric Gastroenterology
- Child Psychiatry
- Health Services Research
Background:
- Increasing incidence and prevalence of inflammatory bowel disease (IBD).
- Rising rates of comorbid psychiatric and behavioral disorders in IBD patients.
- Psychiatric disorders are independent predictors of quality of life in IBD.
Purpose of the Study:
- To analyze the prevalence of psychiatric and behavioral disorders in hospitalized pediatric IBD patients.
- To compare outcomes between IBD patients with and without psychiatric/behavioral disorders.
- To assess the impact of these comorbidities on IBD severity, length of stay, and hospitalization charges.
Main Methods:
- Analysis of non-overlapping years (2003-2016) from the National Inpatient Sample and Kids Inpatient Database.
- Inclusion of all IBD-related hospitalizations for patients under 21 years of age.
- Comparison of IBD patients with and without concomitant psychiatric/behavioral disorder diagnoses.
Main Results:
- A total of 161,294 IBD hospitalizations were analyzed; 15.7% had psychiatric/behavioral disorders.
- Prevalence of these disorders increased from 11.3% (2003) to 20.6% (2016) (p<0.001).
- Psychiatric disorders were associated with increased IBD severity, longer hospital stays (1.17 additional days), and higher charges ($8473 additional).
Conclusions:
- The prevalence of psychiatric and behavioral disorders in hospitalized pediatric IBD patients has significantly increased.
- These comorbidities are independently associated with prolonged hospital stays.
- Higher total hospitalization charges are linked to psychiatric and behavioral disorders in pediatric IBD patients.
Purpose:
The incidence and prevalence of inflammatory bowel disease (IBD) are increasing along with an increasing number of patients with comorbid conditions like psychiatric and behavioral disorders, which are independent predictors of quality of life.
Methods:
Non-overlapping years (2003-2016) of National Inpatient Sample and Kids Inpatient Database were analyzed to include all IBD-related hospitalizations of patients less than 21 years of age. Patients were analyzed for a concomitant diagnosis of psychiatric/behavioral disorders and were compared with IBD patients without psychiatric/behavioral disorder diagnoses for outcome variables: IBD severity, length of stay and inflation-adjusted hospitalization charges.
Results:
Total of 161,294 IBD-related hospitalizations were analyzed and the overall prevalence rate of any psychiatric and behavioral disorders was 15.7%. Prevalence rate increased from 11.3% (2003) to 20.6% (2016), p<0.001. Depression, substance use, and anxiety were the predominant psychiatric disorders. Regression analysis showed patients with severe IBD (odds ratio [OR], 1.57; confidence interval [CI], 1.47-1.67; p<0.001) and intermediate IBD (OR, 1.14; CI, 1.10-1.28, p<0.001) had increased risk of associated psychiatric and behavioral disorders than patients with a low severity IBD. Multivariate analysis showed that psychiatric and behavioral disorders had 1.17 (CI, 1.07-1.28; p<0.001) mean additional days of hospitalization and incurred additional $8473 (CI, 7,520-9,425; p<0.001) of mean hospitalization charges, independent of IBD severity.
Conclusion:
Prevalence of psychiatric and behavioral disorders in hospitalized pediatric IBD patients has been significantly increasing over the last two decades, and these disorders were independently associated with prolonged hospital stay, and higher total hospitalization charges.
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