Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Working Memory01:24

Working Memory

405
Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
405
Visual Agnosia01:12

Visual Agnosia

265
Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
265
Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

106
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
106
Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

195
Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
195

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Severe Mental Illness Longitudinal Evaluation (SMILE): protocol for establishing a cohort and bioresource for UK-based patients with psychosis.

BMJ open·2026
Same author

Tardive Oromandibular Dystonia Associated With Long-Term Intermittent Use of Lurasidone.

Journal of clinical psychopharmacology·2026
Same author

Episode-wide Maudsley staging in treatment-resistant depression: a longitudinal tertiary-care comparison of dimensional and categorical outcomes.

Frontiers in psychiatry·2026
Same author

Saccadic eye movements based classification of patients with obsessive-compulsive disorder, patients with schizophrenia and healthy controls using artificial neural networks.

Cognitive neurodynamics·2026
Same author

Smartwatch-Derived Digital Phenotypes Relate to Psychopathology Dimensions in Patients With Psychotic Spectrum Disorders: Longitudinal Observational Study.

JMIR mental health·2025
Same author

Add-On Pharmacotherapy in Schizophrenia: Does It Improve Long-Term Outcomes? A Systematic Review.

Journal of clinical medicine·2025

Related Experiment Video

Updated: Aug 9, 2025

Virtual Reality Tools for Assessing Unilateral Spatial Neglect: A Novel Opportunity for Data Collection
07:04

Virtual Reality Tools for Assessing Unilateral Spatial Neglect: A Novel Opportunity for Data Collection

Published on: March 10, 2021

4.1K

Spatial and non-spatial feature binding impairments in visual working memory in schizophrenia.

Antigoni Belekou1,2, Mohammad Zia Ul Haq Katshu3,4, Neil Michael Dundon5,6

  • 1Laboratory of Cognitive Neuroscience and Sensorimotor Control, University Mental Health, Neurosciences and Precision Medicine Research Institute "COSTAS STEFANIS", Athens, Greece.

Schizophrenia Research. Cognition
|February 23, 2023
PubMed
Summary

Schizophrenia patients show significant visual working memory deficits, particularly in binding object features and recalling locations. These impairments likely stem from encoding issues rather than memory maintenance problems.

Keywords:
BindingNeurocognitive deficitsSchizophreniaVisual working memory

More Related Videos

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function
06:17

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

2.1K
Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children – Working Memory (CABC-WM)
09:05

Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children – Working Memory (CABC-WM)

Published on: June 12, 2017

29.8K

Related Experiment Videos

Last Updated: Aug 9, 2025

Virtual Reality Tools for Assessing Unilateral Spatial Neglect: A Novel Opportunity for Data Collection
07:04

Virtual Reality Tools for Assessing Unilateral Spatial Neglect: A Novel Opportunity for Data Collection

Published on: March 10, 2021

4.1K
Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function
06:17

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

2.1K
Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children – Working Memory (CABC-WM)
09:05

Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children – Working Memory (CABC-WM)

Published on: June 12, 2017

29.8K

Area of Science:

  • Cognitive Neuroscience
  • Psychiatry
  • Neuroimaging

Background:

  • Working memory (WM) deficits are common in schizophrenia, impacting psychosocial outcomes.
  • Visual and spatial working memory rely on distinct neural networks, suggesting specific deficits in schizophrenia.

Purpose of the Study:

  • To assess visual working memory (vWM) resolution and associative aspects in schizophrenia.
  • To determine if vWM deficits in schizophrenia occur during encoding or maintenance.

Main Methods:

  • 60 participants (30 schizophrenia patients, 30 controls) completed modified object-in-place, delayed non-match-to-sample, and delayed spatial estimation tasks.
  • Tasks assessed visual feature binding, novel object recognition, and spatial recall precision.

Main Results:

  • Schizophrenia patients exhibited lower accuracy in binding visual features and recognizing novel objects.
  • Patients showed reduced precision in recalling memorized target locations.
  • Response set size impacted recognition accuracy more in patients, while delay duration affected tasks similarly across groups.

Conclusions:

  • Schizophrenia is associated with significant visual working memory binding deficits, affecting both spatial and non-spatial information.
  • These impairments appear to originate during the encoding phase of memory rather than maintenance.
  • Binding deficits may be linked to impaired neural functional connectivity in schizophrenia.