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Updated: Aug 9, 2025

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A case of pembrolizumab and lenvatinib as an alterntive therapy for leiomyosarcoma

Naaman Mehta1, Sarah S Lee2, Ghadir Salame3

  • 1Department of Obstetrics and Gynecology, NYU Langone Health, 550 First Avenue, New York, NY 10016, United States.

Gynecologic Oncology Reports
|February 23, 2023
PubMed

Insights

Research on leiomyosarcoma (LMS) treatment is limited. This case report shows disease regression in a patient with recurrent LMS using pembrolizumab and lenvatinib, a combination previously used for endometrial cancer.

Area of Science:

  • Oncology
  • Medical Research

Background:

  • Treatment options for leiomyosarcoma (LMS) are limited.
  • Pembrolizumab and lenvatinib are approved for endometrial cancer but not LMS.
Keywords:
PreventionTherapyUterine sarcoma

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