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Pain Complaints and Intubation Risk in COVID-19: A Retrospective Cohort Study

Connor Martin1, Oluseyi Obadeyi2, Elizabeth Yeo1

  • 1Physical Medicine and Rehabilitation, Loma Linda University Medical Center, Loma Linda, USA.

Cureus
|February 23, 2023
PubMed

Insights

Patients with coronavirus disease 2019 (COVID-19) experiencing abdominal pain face a higher risk of requiring intubation. This finding highlights a critical symptom for COVID-19 severity assessment.

Area of Science:

  • Medicine
  • Infectious Diseases
  • Critical Care

Background:

  • Coronavirus disease 2019 (COVID-19) has caused significant global morbidity and mortality.
  • While COVID-19 treatments and initial presentations are studied, specific symptom-related risks remain unclear.
  • The association between abdominal pain and severe COVID-19 outcomes, specifically intubation, has not been previously established.

Purpose of the Study:

  • To investigate the relationship between reported pain complaints in COVID-19 patients.
  • To determine if specific pain symptoms correlate with increased risk of requiring mechanical ventilation.

Main Methods:

  • Retrospective cohort study of 104 laboratory-confirmed COVID-19 patients.
  • Data collected on emergency room presentation pain complaints between February 1, 2020, and April 27, 2020.
  • Analysis of intubation rates based on reported pain symptoms.

Main Results:

  • The most common pain complaints were chest pain (25.5%), myalgia (23.4%), and abdominal pain (17.0%).
  • Patients reporting abdominal pain had a significantly higher likelihood of intubation (37.5%) compared to those without (8.3%, p=0.001).
  • Headaches (14.9%) and neck/back pain (6.3%) were less common.

Conclusions:

  • Abdominal pain in COVID-19 patients is a significant indicator of increased risk for intubation.
  • Early identification of abdominal pain may aid in predicting severe COVID-19 progression.
  • This finding underscores the importance of considering gastrointestinal symptoms in COVID-19 management.

Keywords:
abdominal paincovid-19covid-gramintubationsars-cov-2 (severe acute respiratory syndrome coronavirus 2)

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