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Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions
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Cardiometabolic Risk and Its Relationship With Visceral Adiposity in Children With Cerebral Palsy

Trevor Batson1, Junsoo Lee1, Joseph M Kindler2

  • 1Department of Kinesiology, University of Georgia, Athens, GA 30602, USA.

Journal of the Endocrine Society
|February 23, 2023
PubMed

Insights

Children with cerebral palsy (CP) show early cardiometabolic disease signs, including higher cholesterol and prediabetes. Increased visceral fat, not reduced physical activity, is the primary driver of these risks in pediatric CP.

Area of Science:

  • Pediatric Cardiology
  • Metabolic Health
  • Neurology

Background:

  • Adults with cerebral palsy (CP) have a higher prevalence of cardiometabolic disease.
  • Research on cardiometabolic disease risk in children with CP is limited.

Purpose of the Study:

  • To determine if children with CP exhibit higher cardiometabolic risk than typically developing children.
  • To examine the relationship between cardiometabolic risk, visceral adiposity, and physical activity in children with CP.

Main Methods:

  • Compared 30 ambulatory children with CP to 30 typically developing controls.
  • Assessed blood lipids, glucose, HOMA-IR, visceral fat (VFMI), and physical activity (accelerometers).

Main Results:

  • Children with CP had higher cholesterol, glucose, dyslipidemia, prediabetes, and VFMI, with lower physical activity than controls.
  • Non-HDL-C and glucose correlated with VFMI; Non-HDL-C and HOMA-IR correlated with physical activity.
  • HOMA-IR strongly correlated with VFMI in children with CP.

Conclusions:

  • Children with CP show early cardiometabolic disease markers.
  • Increased visceral adiposity is more strongly linked to cardiometabolic risk than reduced physical activity in pediatric CP.
Abstract

Keywords:
cardiometabolic diseasecerebral palsydyslipidemiaprediabetesvisceral fat

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