Ozone therapy: protocol for treating canine parvovirus infection

Area of Science:

• Veterinary Medicine
• Infectious Diseases
• Complementary Therapies

Background:

• Canine Parvovirus (CPV) causes severe hemorrhagic gastroenteritis, particularly in unvaccinated puppies.
• Current CPV treatment relies on supportive care due to the absence of specific antiviral drugs.
• Ozone therapy offers potential benefits including antimicrobial, regenerative, and anti-inflammatory effects.

Purpose of the Study:

• To evaluate the efficacy of ozone therapy as a complementary treatment for Canine Parvovirus infection in dogs.
• To compare the clinical outcomes of CPV-infected dogs receiving supportive care versus supportive care plus ozone therapy.

Main Methods:

• Four CPV-positive puppies (2-3 months old) were randomly assigned to a control group (supportive care) or an experimental group (supportive care + ozonated Ringer's Lactate).
• Clinical signs including emesis, diarrhea, weight, hydration, blood glucose, abdominal pain, and blood count were monitored over 48 hours.
• Ozone therapy involved intravenous administration of 500 mL of ozonated Ringer's Lactate solution.

Main Results:

• One puppy in the control group did not survive.
• Puppies receiving ozone therapy exhibited faster resolution of diarrhea and reduced hospitalization duration compared to the control survivor.
• The experimental group showed improved clinical signs and recovery rates.

Conclusions:

• Ozone therapy, as an adjunct to conventional supportive care, demonstrated promising results in managing Canine Parvovirus infection.
• Further research is warranted to confirm the therapeutic benefits and optimal protocols for ozone therapy in canine parvoviral gastroenteritis.