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The Charlson comorbidity index and short-term readmission in patients with heart failure: A retrospective cohort

Dongmei Wei1,2, Yang Sun3, Rongtao Chen3

  • 1Department of Cardiovascular, Guangzhou University of Chinese Medicine First Affiliated Hospital, Guangzhou, China.

Medicine
|February 23, 2023
PubMed

Insights

The Charlson Comorbidity Index (CCI) predicts heart failure readmissions. Higher CCI scores significantly increase the risk of short-term readmission in heart failure patients.

Area of Science:

  • Cardiology
  • Health Services Research

Background:

  • The Charlson Comorbidity Index (CCI) is a widely used measure of disease burden.
  • Its association with short-term readmission in heart failure (HF) patients remains unclear.

Purpose of the Study:

  • To investigate the independent relationship between the CCI and short-term readmission in HF patients.
  • To determine the predictive value of CCI for clinical outcomes in HF.

Main Methods:

  • A cohort of 2008 HF patients was studied from December 2016 to June 2019.
  • Patients were categorized by CCI (low < 3, high >= 3).
  • Multivariable logistic regression and 2-piece linear regression models were used for analysis.

Main Results:

  • Patients with a high CCI exhibited a higher risk of short-term readmission.
  • A curvilinear association was observed between CCI and readmission, with a saturation point at CCI 2.97.
  • For CCI scores > 2.97, readmission risk significantly increased (OR, 2.66; 95% CI, 1.566-4.537).

Conclusions:

  • A high CCI is significantly associated with increased short-term readmission in HF patients.
  • The CCI demonstrates predictive value for clinical outcomes and readmission rates in HF.
  • CCI can aid in estimating readmission risk for heart failure patients.

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