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Updated: Aug 9, 2025

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
Published on: March 26, 2015
Heterotopic Ossification After Anterior Cruciate Ligament Reconstruction With Quadriceps Tendon Autograft: A Case
Jack T Bragg1, Madison Hayes-Lattin2, Margaret V Shields1
1Department of Orthopaedic Surgery, Tufts Medical Center, Boston, Massachusetts.
Case:
A 32-year-old healthy woman tore her right anterior cruciate ligament (ACL) and underwent reconstruction with quadriceps tendon autograft. Twelve weeks postoperatively, she had anterior thigh pain limiting knee flexion and a palpable mass in the anterior thigh. Imaging revealed a calcified mass near the graft site, concerning for heterotopic ossification (HO). After maturation of the heterotopic bone, she underwent debridement and HO removal.
Conclusion:
This is a case of HO at the quadriceps tendon autograft site after ACL reconstruction. When counseling patients, clinicians should be mindful of this possible complication and its treatment.
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