Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Nephrotic Syndrome II : Assessment and Medical Management

Nephrotic Syndrome II : Assessment and Medical Management

IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...

Chronic Kidney Disease III: Interprofessional Care

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...

Renal Regulation of Acid-Base Balance

Renal Regulation of Acid-Base Balance

Metabolic reactions in the body produce nonvolatile acids, such as sulfuric acid, which generate an acid load of approximately 1 mEq of H+ per kilogram of body weight daily. Excreting H+ in the urine is essential to balance this acid load.
In the kidneys, cells within the proximal convoluted tubules (PCT) and the collecting ducts secrete hydrogen ions (H+) into the tubular fluid. Specifically, in the PCT, Na+/H+ antiporters secrete H+ while reabsorbing Na+.
However, the intercalated cells in...

Nephrotic Syndrome I : Introduction

Nephrotic Syndrome I : Introduction

Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Renovascular disease induces functionally relevant, locus-specific alterations to DNA methylation and hydroxymethylation in swine scattered tubular-like cells.

American journal of physiology. Renal physiology·2026

Same author

Establishing a core outcome measure for cancer in trials in kidney transplantation: a standardized outcomes in nephrology-kidney transplantation consensus workshop report.

Transplant international : official journal of the European Society for Organ Transplantation·2026

Same author

AKI After Hepatic Histotripsy.

Kidney international reports·2026

Same author

Phosphate Disorders in Cancer.

Kidney360·2026

Same author

Periodontal disease and diabetic kidney disease: A comprehensive analysis.

Disease-a-month : DM·2026

Same author

Oral Phageome as Potential Modulators of Periodontal Dysbiosis. A Systematic Review.

Oral diseases·2026

Same journal

Impact of APOL1-Associated Pregnancy Complications on Kidney Disease Phenotypes in a HIV-Associated Nephropathy Mouse Model.

Kidney360·2026

Same journal

Risk Prediction of 2-Year Incident Cognitive Impairment in Maintenance Hemodialysis Patients: A Multicenter Prospective Cohort Study.

Kidney360·2026

Same journal

Anti-Glomerular Basement Membrane Nephritis Post-Renal Transplant in Alport Syndrome Patients.

Kidney360·2026

Same journal

Non-Classical Monocyte Expansion Is Independently Associated with Anemia Severity in Patients with ESKD: The Immunity in End-Stage Renal Disease Cohort-Study.

Kidney360·2026

Same journal

Adult-Onset Hereditary Thrombotic Thrombocytopenic Purpura Presenting as Kidney Failure: A Heterozygous ADAMTS13 Variant and Possible Modifying Polymorphisms.

Kidney360·2026

Same journal

Impact of Prior Adverse Pregnancy Outcome on Kidney Structure and Function in Kidney Donors.

Kidney360·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Aug 9, 2025

Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography

Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography

Published on: June 21, 2024

Onconephrology 2022: An Update.

Marco Bonilla¹, Prakash Gudsoorkar², Rimda Wanchoo³

¹Section of Nephrology, Department of Medicine, University of Chicago, Chicago, Illinois.

|February 23, 2023

Summary

This summary is machine-generated.

Onconephrology, a growing field merging oncology and nephrology, is crucial for managing kidney issues from cancer therapies. This review covers recent advances in understanding and treating these kidney-related adverse events.

More Related Videos

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes

Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes

Published on: March 4, 2022

Related Experiment Videos

Last Updated: Aug 9, 2025

Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography

Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography

Published on: June 21, 2024

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes

Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes

Published on: March 4, 2022

Area of Science:

Onconephrology
Nephrology
Hematology/Oncology

Background:

Onconephrology is an emerging subspecialty at the intersection of nephrology and hematology/oncology.
Understanding cancer immunobiology and oncotherapeutic drug toxicities is vital for nephrologists.
Recent years have seen significant advancements in recognizing kidney-related adverse events from novel cancer treatments.

Conclusions:

Onconephrology is a rapidly evolving field requiring specialized knowledge.
Recent research has significantly improved understanding of kidney complications in cancer patients.
Continued investigation is essential for optimizing patient care in onconephrology.