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Updated: Aug 9, 2025

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb
Published on: January 17, 2025
[Exploring the significance of chemotherapy in the perioperative application of biliary tract carcinomas]
1Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, China.
Abstract:
Biliary tract cancer is extremely malignant with a poor prognosis. At the moment, the only curative method available is radical resection. Targeted and immunotherapy are currently advancing rapidly, but chemotherapy still holds a key role in the perioperative treatment of biliary cancer. Perioperative chemotherapy aims to decrease tumor volume prior to surgery so that patients can have their tumors surgically removed or have a higher radical resection rate. It also aims to remove any remaining tumor cells after surgery and prevent the growth of new tumors. Combination treatments based on chemotherapy have been increasingly investigated in recent years to improve perioperative care and patient survival. From the point of view of chemotherapy regimens and clinical trial success in the perioperative phase of radical surgery, the value of chemotherapy in the perioperative period of biliary tract cancer was explored in this paper.

