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Related Concept Videos

Ankle Joint01:10

Ankle Joint

1.7K
The ankle is formed by the talocrural joint (crural = leg). It consists of the articulations between the talus bone of the foot and the distal ends of the tibia and fibula of the leg. The superior aspect of the talus bone is square-shaped and has three areas of articulation. The top of the talus articulates with the inferior tibia. This is the portion of the ankle joint that carries the body weight between the leg and foot. The sides of the talus are firmly held in position by the articulations...
1.7K

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Related Experiment Video

Updated: Aug 9, 2025

A Mouse Model of Ankle-Subtalar Complex Joint Instability
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A Mouse Model of Ankle-Subtalar Complex Joint Instability

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Current Challenges in Chronic Ankle Instability: Review and Perspective.

Matthieu Lalevée1, Donald D Anderson2, Jason M Wilken3

  • 1CETAPS EA3832, Research Center for Sports and Athletic Activities Transformations, University of Rouen Normandy, F-76821 Mont-Saint-Aignan, France; Department of Orthopedic Surgery, Rouen University Hospital, 37 Bd Gambetta, Rouen 76000, France.

Foot and Ankle Clinics
|February 23, 2023
PubMed
Summary

Chronic ankle instability (CAI) is a common and disabling condition with limited treatment options. Further research is needed to understand its multifaceted nature, linking mechanical and functional aspects for better outcomes.

Keywords:
Ankle instabilityAnkle sprainFunctionalMechanicalRisk factors

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Area of Science:

  • Orthopedics
  • Sports Medicine
  • Biomechanics

Background:

  • Chronic ankle instability (CAI) is prevalent and poses a significant socioeconomic burden.
  • Current treatments for CAI often lack sufficient efficacy.
  • CAI is complex, often viewed separately as mechanical instability or functional impairment, despite their interconnectedness.

Purpose of the Study:

  • To review existing literature and identify risk factors for CAI.
  • To provide perspectives and opinions for future research directions in CAI.
  • To emphasize the need for integrated research addressing both mechanical and functional aspects of CAI.

Main Methods:

  • A comprehensive literature review was conducted.
  • Identification of key risk factors associated with CAI.
  • Synthesis of current understanding and future research perspectives.

Main Results:

  • Identified various risk factors contributing to CAI.
  • Highlighted the limitations of current treatment strategies.
  • Emphasized the critical link between mechanical instability and functional deficits.

Conclusions:

  • There is a need for basic research to advance translational studies in CAI.
  • Future research should adopt a holistic approach, integrating mechanical and functional assessments.
  • Developing more efficacious treatments requires a deeper understanding of CAI's multifactorial etiology.